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Case studies

Below you find a selection of case studies which highlight how innovative technologies can truly benefit people, healthcare systems and society at large.

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  • Transcatheter Aortic Valve Implantation (TAVI)

    Aortic stenosis is the narrowing of the aortic valve opening in the heart, which limits the amount of blood flow from the left ventricle to the aorta. Patients with aortic stenosis may exhibit symptoms including chest pain, fatigue, shortness of ...
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  • Evaluation of lungs outside the body before transplantation

    Lung transplantation, as a therapy for the management of end-stage lung disease, is not always possible given that there are more people in need of a new lung than there are donated lungs available. Today; only about ...
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The value of retinal prostheses

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  • This Retinal Prosthesis System is the only FDA & CE approved treatment in the world for Retinitis Pigmentosa, an orphan disease that causes irremediable blindness.
  • Retinitis Pigmentosa affects one in every 4,000 people in US & Europe.
  • The system captures images from a miniature video camera. Based on these images, electrical signals are sent to patients’ retina, allowing them to perceive visual information.
  • The technology improves patients’ orientation and mobility capability in daily life and provides them with the chance to enjoy experiences which would have been impossible only a few years ago.
  • Both hard- and software can be upgraded throughout the lifetime of the device.

Transcatheter Aortic Valve Implantation (TAVI)

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Aortic stenosis is the narrowing of the aortic valve opening in the heart, which limits the amount of blood flow from the left ventricle to the aorta. Patients with aortic stenosis may exhibit symptoms including chest pain, fatigue, shortness of breath, light- headedness, fainting and difficulty exercising. Once aortic stenosis becomes severe and symptoms develop, it is life- threatening. When aortic stenosis is left untreated, it can lead to pulmonary hypertension, heart attack or sudden death. Half of people with untreated severe aortic stenosis will die within an average of two years after the onset of symptoms.

Evaluation of lungs outside the body before transplantation

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Lung transplantation, as a therapy for the management of end-stage lung disease, is not always possible given that there are more people in need of a new lung than there are donated lungs available. Today; only about 20% of the donated lungs are accepted for transplantation. The main reason for this low figure is the fact that patients, before becoming a donor, often have to undergo treatment which negatively affects the organ.

Renal denervation for treatment-resistant hypertension

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Treatment-resistant hypertension is defined as blood pressure that remains high (>140/90mmHg) despite treatment with three or more antihypertensive medications. Renal denervation (RDN) therapy is a minimally invasive, catheter-based procedure that modulates the output of nerves that line the walls sympathetic nervous system, which affects the major organs that are responsible for regulating blood pressure: the brain, the heart, the kidneys and the blood vessels.

Implantable pump for treatment of refractory ascites

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Chronic accumulation of excess fluid in the abdomen, called ascites, is a common complication among patients with late-stage liver disease and certain cancers. Ascites that does not respond to medical treatment, called refractory ascites, affects more than 100,000 patients in Europe and the US every year, and is growing by 10% each year due to a rise in the number of hepatitis and obesity-related liver disease patients.

Remote monitoring of cardiac implantable electronic device therapy

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It is quite likely that you have a close relative, or know someone, who suffers from heart failure. It is estimated that in elderly people between 75 and 84 years, 1 in 15 does so. Heart failure is associated with poor life expectancy and symptoms such as breathlessness and fatigue.

Performing interventional cardiology using an FFR measurement system

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Coronary artery disease is the most common type of cardiovascular disease, affecting millions of people worldwide. It is caused by a narrowing or blocking of the arteries which restricts blood flow and reduces the amount of oxygen to the heart. According to the European Heart Network (EHN), the financial burden for EU health care systems related to cardiovascular diseases has been estimated to be just under € 110 billion (2006).

Woundcare using an innovative surgical cover dressing

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Total joint arthroplasty (TJA), also called joint replacement, is a common procedure today most often involving the knee or hip. While surgical site infections (SSIs) are major risks for all surgery patients, it is widely recognised as a significant risk in TJA, including total knee arthroplasty (TKA) and total hip arthroplasty (THA). SSIs are considered to be a major healthcare issue in many countries around the world. In developing countries, SSIs are the most common healthcare acquired infections and affect up to two thirds of all operated patients.